Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS

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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Revenue        
Total revenue, net $ 55,779 $ 14,667 $ 105,595 $ 22,201
Operating expenses        
Cost of sales 2,447 254 4,302 610
Selling, general and administrative 52,169 44,645 148,898 128,772
Research and development 10,973 20,066 35,118 39,990
Other (income) expense, net (311) 55 647 859
Total cost of sales and operating expenses 65,278 65,020 188,965 170,231
Loss from operations (9,499) (50,353) (83,370) (148,030)
Interest income 1,464 106 2,209 420
Net loss before income taxes (8,035) (50,247) (81,161) (147,610)
Income tax expense 954 8 973 34
Net loss (8,989) (50,255) (82,134) (147,644)
Other comprehensive loss:        
Unrealized gain (loss) on available-for-sale securities, net of tax of nil 326 (2) (675) 11
Comprehensive loss $ (8,663) $ (50,257) $ (82,809) $ (147,633)
Basic loss per share ($ per share) $ (0.06) $ (0.39) $ (0.58) $ (1.15)
Diluted loss per share ($ per share) $ (0.06) $ (0.39) $ (0.58) $ (1.15)
Weighted-average common shares outstanding used in computation of basic loss per share (in shares) 141,856 128,443 141,831 128,084
Weighted-average common shares outstanding used in computation of diluted loss per share (in shares) 141,856 128,443 141,831 128,084
Product revenue, net        
Revenue        
Total revenue, net $ 25,502 $ 14,638 $ 75,142 $ 22,113
License and collaboration revenue        
Revenue        
Total revenue, net $ 30,277 $ 29 $ 30,453 $ 88