Annual reports filed by certain Canadian issuers pursuant to Section 15(d) and Rule 15d-4

Subsequent event (Details)

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Subsequent event (Details)
2 Months Ended 12 Months Ended
Feb. 14, 2014
USD ($)
Mar. 15, 2019
USD ($)
shares
Mar. 15, 2019
CAD ($)
shares
Dec. 31, 2018
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Disclosure of non-adjusting events after reporting period [line items]          
Net proceeds from issuance of common shares       $ 0 $ 162,324,000
Share issue related cost         $ 10,780,000
Granted pursuant to Stock Option Plan (in shares) | shares       3,003,000 2,729,000
Number of share options exercised in share-based payment arrangement | shares       276,000 1,494,000
Exercise price, share options granted       $ 5.29 $ 4.12
Warrants          
Disclosure of non-adjusting events after reporting period [line items]          
Number of warrants exercised | shares       1,172,000 85,000
Derivative warrant liabilities       $ 6,271,000  
Warrants | Private Placement Offering Feb 14 2014          
Disclosure of non-adjusting events after reporting period [line items]          
Net proceeds from issuance of common shares $ 52,000,000        
Number of warrants exercised | shares       0 27,000
Issued pursuant to exercise of warrants (in shares) | shares         1,154,000
Number of cashless warrants exercised (in shares) | shares         1,983,000
Major ordinary share transactions          
Disclosure of non-adjusting events after reporting period [line items]          
Proceeds from issuing shares   $ 1,304,000      
Granted pursuant to Stock Option Plan (in shares) | shares   1,365,000 1,365,000    
Issued pursuant to exercise of stock options (in shares) | shares   377,000 377,000    
Number of share options exercised in share-based payment arrangement | shares   377,000 377,000    
Exercise price, share options granted   $ 6.06 $ 8.04    
Major ordinary share transactions | Common shares | ATM Facility          
Disclosure of non-adjusting events after reporting period [line items]          
Net proceeds from issuance of common shares   $ 30,000,000      
Number of shares issued | shares   4,608,000 4,608,000    
Weighted average share price   $ 6.55      
Share issue related cost   $ 1,170,000      
Commission rate   3.00% 3.00%    
Commission paid to agent, controlled equity offerings   $ 900,000      
Commission paid for professional and filing fees   270,000      
Major ordinary share transactions | Warrants | Private Placement Offering Feb 14 2014          
Disclosure of non-adjusting events after reporting period [line items]          
Proceeds from issuing shares   $ 1,494,000      
Number of warrants exercised | shares   1,738,000 1,738,000    
Exercise price of warrants exercised   $ 3.2204      
Issued pursuant to exercise of warrants (in shares) | shares   464,000 464,000    
Number of shares issued from cashless warrants exercised (in shares) | shares   687,000 687,000    
Number of cashless warrants exercised (in shares) | shares   1,274,000 1,274,000    
Transfer of derivative warrant liability to equity   $ 5,919,000      
Derivative warrant liability adjustment   $ 352,000