Annual reports filed by certain Canadian issuers pursuant to Section 15(d) and Rule 15d-4

Supplementary cash flow information - Other Operating Assets and Liabilities (Details)

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Supplementary cash flow information - Other Operating Assets and Liabilities (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Supplementary Cash Flow Information [Abstract]    
Accounts receivable and accrued interest receivable $ (108) $ (23)
Prepaid expenses, deposits and other (5,094) 2
Adjustments for increase (decrease) in clinical trail deposits 90 (448)
Clinical trial contract deposits (888) 2,168
Net change in other operating assets and liabilities (note 17) (6,000) 1,699
Interest received $ 2,148 $ 973