Annual reports filed by certain Canadian issuers pursuant to Section 15(d) and Rule 15d-4

Nature of expenses - Research and development (Details)

v3.19.1
Nature of expenses - Research and development (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Expenses by nature [abstract]    
Contract research organizations (CROs) and other third party clinical trial expenses $ 27,923 $ 21,634
Drug supply and distribution 4,893 7,124
Salaries, incentive pay and employee benefits 4,260 3,065
Stock compensation expense 2,697 993
Travel, insurance, patent annuity fees, legal fees and other 1,609 1,114
Research and development expense $ 41,382 $ 33,930